Exploring a New Frontier in Regenerative Skin Rejuvenation

In the world of aesthetic medicine, the pursuit of luminous, youthful skin is continually evolving. Among the latest innovations gaining attention is a treatment often described as the salmon sperm microneedling facial

At first glance, the term may prompt curiosity,  how can something derived from salmon sperm contribute to healthy skin renewal?

The answer lies in modern regenerative science coupled with expertly applied microneedling techniques. At Dr. John Diaz’s Beverly Hills practice, this approach is administered with careful attention to safety, purity, and results.

Understanding the Origins: What Are Polynucleotides and Why Is Salmon Sperm DNA Used?

The key active elements in this facial are known as polynucleotides (PNs) or polydeoxyribonucleotides (PDRN) are fragments of DNA derived from purified sources, in this case, from salmon sperm tissue. These molecules are biocompatible, meaning human skin recognizes and responds favorably to them.

Research in aesthetic medicine has shown that polynucleotides can improve skin texture, hydration, and repair the extracellular matrix of the skin. Rather than masking signs of aging, they stimulate regeneration at a cellular level, encouraging skin to repair and rebuild itself.

The Science of Regeneration: How Polynucleotides Stimulate Skin Renewal

Microneedling creates controlled micro-injuries that trigger your body’s natural healing mechanism by stimulating fibroblast activity, collagen production, and skin barrier renewal. 

When combined with polynucleotides, the effects are amplified.

Polynucleotides:

In simple terms, this combination promotes regeneration from within, resulting in stronger, smoother, and more radiant skin.

Why Combine It with Microneedling: Maximizing Skin Renewal Results

Microneedling alone is powerful, but when paired with polynucleotides, results reach a new level.

How the combination works:

At our Beverly Hills practice, we integrate this combination into advanced facial rejuvenation protocols.

👉 Learn more: Microneedling in Beverly Hills

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Key Benefits Patients Notice

Patients report:

What to Expect During the Facial

1. Consultation and assessment

Your treatment begins with a full skin evaluation and a personalized plan.

2. Preparation and numbing

Topical numbing cream ensures a comfortable experience.

3. Microneedling phase

A sterile device creates controlled microchannels across the skin.

4. Application of the polynucleotide solution

The purified salmon DNA serum is applied while the microchannels are open, enhancing absorption.

5. Calming and protection

A soothing mask and barrier cream are applied to support the healing process.

6. Post-treatment recovery

Mild redness or warmth may last 12–48 hours. Most patients return to social activities within a day or two.

7. Visible results timeline

Early glow: 1–2 weeks.

Firmness and tone improvement: 4–6 weeks.

Optimal results: after 2–3 sessions spaced a month apart.

Safety, Purity, and Clinical Integrity

The term “salmon sperm” can sound unusual, but this treatment uses highly purified DNA that is sterile and biocompatible.

Clinical studies show improvements in elasticity, hydration, and texture with minimal side effects.

Dr. Diaz ensures the highest standards of safety:

Who Is a Good Candidate

This facial is ideal for adults seeking visible rejuvenation with minimal downtime. 

It’s ideal for:

Not suitable for: active infections, pregnancy, or certain medical conditions.

Comparing Polynucleotide Therapy to PRP and Exosomes

Each regenerative approach offers unique advantages:

The Beverly Hills Experience: Luxury Care Rooted in Science

At Dr. John Diaz’s Beverly Hills clinic, every treatment combines artistry with advanced medical science. The goal is not only rejuvenation but confidence and natural balance.

Each patient receives:

Frequently Asked Questions

Is this really made from salmon sperm?

Yes, the polynucleotides are derived from salmon DNA but are purified, sterilized, and biocompatible, not biological tissue.

How many treatments will I need?

Most patients benefit from 2–3 sessions spaced 4–6 weeks apart, followed by maintenance every 6–12 months.

Is there downtime?

Mild redness and warmth may occur for 1–2 days, but makeup and normal activities can resume quickly.

Are results immediate?

You’ll notice radiance within a week, with firmer, smoother skin over the next 4–6 weeks.

Safe for all skin types?

Generally, yes, but a consultation ensures compatibility for your skin tone and condition.

What are the risks?

Minimal, such as mild redness, sensitivity, or tiny scabs that fade quickly.

Can it replace other treatments?

It complements rather than replaces lasers, fillers, or surgery, and works beautifully within a full-spectrum rejuvenation plan.

How long do results last?

Improvements last 9–12 months, depending on lifestyle and skincare.

Final Thoughts: Regenerative Beauty Backed by Science

The Salmon Sperm Microneedling Facial bridges modern science and artistry to restore radiance from within. At Dr. John Diaz’s Beverly Hills practice, every treatment is designed to enhance the patient’s natural features while optimizing the skin’s function.To explore this cutting-edge facial and start your personalized rejuvenation journey, request your consultation today.

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Visit Us In Beverly Hills

Our Location

465 N Roxbury Dr Penthouse, Beverly Hills, CA 90210

Hours of Operation

Monday-Friday: 8:00 AM - 5:00 PM

Contact Us

424.278.2214